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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP25 All Species: 29.09
Human Site: S130 Identified Species: 71.11
UniProt: Q9UHP3 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHP3 NP_037528.3 1087 125750 S130 T D E E Q A I S R V L E A S I
Chimpanzee Pan troglodytes XP_531393 1087 125791 S130 T D E E Q A I S R V L E A S I
Rhesus Macaque Macaca mulatta XP_001107973 1166 134796 S209 T D E E Q A I S R V L E A S I
Dog Lupus familis XP_535562 1085 125476 S130 T D E E Q A I S R V L E A S I
Cat Felis silvestris
Mouse Mus musculus P57080 1055 121402 S130 T D E E Q A I S R V L E A S I
Rat Rattus norvegicus NP_001100584 1055 121573 S131 T D E E Q A I S R V L E A S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514451 1105 126985 S181 T D E E Q A I S R V L E A S I
Chicken Gallus gallus Q5ZID5 1047 118729 S131 S P E H K N R S K R K R C E V
Frog Xenopus laevis NP_001086746 1046 121273 R130 D E E Q A I S R V L E A S I A
Zebra Danio Brachydanio rerio NP_001001886 1072 123104 R130 D E E Q A I S R V L E A S I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 92.2 97.5 N.A. 91.1 91.5 N.A. 81.5 46.8 79.3 74.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 92.8 98.8 N.A. 93.7 94.1 N.A. 86.7 64.1 86.8 84.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 13.3 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 40 33.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 20 70 0 0 0 0 0 20 70 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 20 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 20 100 70 0 0 0 0 0 0 20 70 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 20 70 0 0 0 0 0 0 20 70 % I
% Lys: 0 0 0 0 10 0 0 0 10 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 20 70 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 20 70 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 20 70 10 0 10 0 0 0 % R
% Ser: 10 0 0 0 0 0 20 80 0 0 0 0 20 70 0 % S
% Thr: 70 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 20 70 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _